Table 4.
Parasitaemia and prevalence of malaria infection and anaemia at days 0, 7 and 17
| Day 0 N = 163 (95% CI)a [n] | Day 7 N = 152 (95% CI) [n] | Day 17 N = 148 (95% CI) [n] | ||
|---|---|---|---|---|
| Parasitaemia (parasites μL−1) | Geometric mean | 1640·4 (1298·1–2073·0) | 578·7 (351·0–954·2) | 457·7 (185·2–1131·1) |
| Range | 20–90 640 | 31·4–10 360 | 5·4–101 080 | |
| Prevalence by microscopy (%) | Any parasitaemia | 100 (97·8–100) [163] | 26·3 (19·5–34·1) [40] | 22·3 (15·9–29·9) [33] |
| 1–500 (parasites μL−1) | 18·4 (12·8–25·2) [30] | 9·9 (5·6–15·8) [15] | 10·1 (5·8–16·2) [15] | |
| 500–2000 (parasites μL−1) | 37·4 (30·0–45·3) [61] | 9·9 (5·6–15·8) [15] | 8·1 (4·3–13·7) [12] | |
| 2000–10 000 (parasites μL−1) | 33·1 (26·0–40·9) [ 54] | 5·9 (2·7–10·9) [9] | 0·7 (0·01–3·7) [1] | |
| >10 000 (parasites μL−1) | 11·1 (6·7–16·9) [18] | 0·7 (0·02–3·6) [1] | 3·4 (1·1–7·7) [5] | |
| PCR-corrected (P. falciparum only) | – | 21·9 (15·5–29·3)b [33] | 11·7 (7·0–18·1)c [17] | |
| Prevalence by real-time PCR (%) | P. falciparum | 96·9 (93·0–99·0) [158] | 50·0 (41·8–58·2) [76] | 39·2 (31·3–47·5) [58] |
| P. malariae | 49·7 (41·8–57·6) [81] | 12·5 (7·7–18·8) [19] | 6·1 (2·8–11·2) [9] | |
| P. ovale spp. | 17·8 (12·3–24·5) [29] | 5·3 (2·3–10·1) [8] | 2·0 (0·4–5·8) [3] | |
| Prevalence of mixed infections by real-time PCR (%) | P. falciparum/P. malariae | 41·1 (33·5–49·1) [67] | 10·5 (6·1–16·5) [16] | 5·4 (2·4–10·4) [8] |
| P. falciparum/P. ovale spp. | 9·2 (5·2–14·7) [15] | 3·3 (1·1–7·5) [5] | 1·4 (0·2–4·8) [2] | |
| P. falciparum/P. malariae/P. ovale spp. | 8·0 (4·3–13·3) [13] | 1·3 (0·2–4·7) [2] | 0·7 (0·01–3·7) [1] | |
| Prevalence of anaemia (%) | Any anaemia | 56·4 (48·5–64·2) [92] | 45·4 (37·3–53·7) [69] | 14·9 (9·6–21·6) [22] |
| Mild | 27·6 (20·1–35·1) [45] | 27·6 (20·1–35·5) [42] | 10·8 (6·3–17·0) [16] | |
| Moderate | 27·6 (20·1–35·1) [45] | 17·8 (12·0–24·8) [27] | 4·1 (1·5–8·6) [6] | |
| Severe | 1·2 (0·1–4·4) [2] | 0 | 0 |
95% CI = 95% confidence interval.
N = 151.
N = 145.