Figure 3.

Schematic representation of a simplified regional citrate anticoagulation protocol for SLED using a calcium-containing dialysate. Detailed protocol is shown as supplemental material in ref. 51. *Sampling for systemic ionized calcium is from the circuit arterial line or the patient’s arterial line (to avoid the effects of vascular access recirculation). Systemic total calcium can be measured from a central venous line. ACD-A, anticoagulant citrate dextrose solution A; SLED, sustained low-efficiency dialysis; Uf, ultrafiltration.