Table 4.
Hazard ratios for telomeric G-tail length and total telomere length with cardiovascular events in patients
| Model | Covariate | Cardiovascular Events | |
|---|---|---|---|
| HR (95% CI) | P Value | ||
| Telomeric G-tail | |||
| 1 | Crude (per log rlu) | 0.12 (0.03 to 0.50) | 0.004 |
| 2 | 1 plus age, sex, and diabetes mellitus | 0.16 (0.04 to 0.65) | 0.01 |
| 3 | 2 plus baseline CVD and inflammation | 0.18 (0.04 to 0.78) | 0.02 |
| 4 | 3 plus vitamin D use, phosphate, and intact PTH | 0.14 (0.03 to 0.63) | 0.01 |
| Total telomeres | |||
| 1 | Crude (per log rlu) | 0.39 (0.08 to 1.31) | 0.12 |
| 2 | 1 plus age, sex, and diabetes mellitus | 0.50 (0.11 to 2.14) | 0.35 |
| 3 | 2 plus baseline CVD and inflammation | 0.48 (0.11 to 2.11) | 0.33 |
| 4 | 3 plus vitamin D use, phosphate, and intact PTH | 0.25 (0.05 to 1.28) | 0.10 |
Indicated are crude HRs or with various degrees of adjustment (models 2–4) for cardiovascular events according to telomeric G-tail and total telomere length. Inflammation was defined as C-reactive protein >0.5 mg/dl. HR, hazard ratio.