Table 2.
Top ten pathways ranked by Z-score (T2D and pancreatic islets dataset)
| Rank | Pathway | Z-score |
|---|---|---|
| 1 | Arachidonic acid metabolism | 6.103672 |
| 2 | TGF-beta signaling pathway | 5.571651 |
| 3 | Complement and coagulation cascades | 5.468563 |
| 4 | PPAR signaling pathway | 5.302763 |
| 5 | Cytokine-cytokine receptor interaction | 5.102405 |
| 6 | Fatty acid metabolism | 5.050608 |
| 7 | Intestinal immune network for IgA production | 4.748036 |
| 8 | Cell adhesion molecules (CAMs) | 4.601507 |
| 9 | Allograft rejection | 4.480696 |
| 10 | Staphylococcus aureus infection | 4.416682 |