Table 1.
Association of miR-149 expression with clinicopathologic features of 130 hepatocellular carcinoma patients
| Clinicopathologic features | Case | miR-149-low (n, %) | P |
|---|---|---|---|
| Age (years) | |||
| ≤50 | 72 | 38 (52.78) | NS |
| >50 | 58 | 32 (55.17) | |
| Gender | |||
| Male | 96 | 50 (52.08) | NS |
| Female | 34 | 20 (58.82) | |
| Serum AFP | |||
| Positive | 72 | 42 (58.33) | NS |
| Negative | 58 | 28 (48.28) | |
| Tumor stage | |||
| T1 | 23 | 6 (26.09) | 0.01 |
| T2 | 40 | 15 (37.50) | |
| T3 | 52 | 34 (65.38) | |
| T4 | 15 | 15 (100.00) | |
| Tumor grade | |||
| G1 | 31 | 16 (51.61) | NS |
| G2 | 76 | 39 (51.32) | |
| G3 | 23 | 15 (65.22) | |
| Growth pattern | |||
| Trabecular | 101 | 53 (52.48) | NS |
| Nontrabecular | 29 | 17 (58.62) | |
| Cirrhosis | |||
| Yes | 86 | 45 (52.33) | NS |
| No | 44 | 25 (56.82) | |
| Underlying liver disease | |||
| Alcoholic | 25 | 13 (52.00) | NS |
| Hepatitis B | 49 | 28 (57.14) | |
| Hepatitis C | 35 | 17 (48.57) | |
| Unknown | 21 | 12 (57.14) |
Note: ‘NS’ refers to the differences among groups have no statistical significance.