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. Author manuscript; available in PMC: 2015 Nov 6.
Published in final edited form as: Cell. 2014 Nov 6;159(4):789–799. doi: 10.1016/j.cell.2014.09.053

Figure 7. Addition of Christensenella minuta to donor stool leads to reduced weight and adiposity gains in recipient mice.

Figure 7

A: Box plot of percent weight change for germfree mouse recipients of a single donor stool only (lacking detectable Christensenella in unrarefied 16S rRNA data) or the donor stool amended with live C. minuta. B: Box plots showing percent body fat for mice in each group at Day 21 N = 12 mice per treatment. C, D: Principal coordinates analysis of unweighted UniFrac distances for (i) the inoculum prior to transplantation, (ii) fecal samples at 5 time points post-transplant; see panel legend for color key. The amount of variance described by the first two PCs is shown on the axes. The same data projection is shown in panels C and D; sample symbols are colored by time point (C) and by treatment (D). E: Relationship between PCs from the PCoA analysis and levels of Oscillospira at Day 21 (rho = −0.71, P = P < 0.001). Symbols are colored by treatment. Relates to Figure S6.