Table 6.
Frequency of different neuropsychiatric comorbidities in patients with dementia with Lewy bodies (n = 634) versus Alzheimer’s disease patients (n = 9,161) within different subgroups regarding gender, cognitive level at the time of diagnosis and living place using the chapters of the International Statistical Classification of Diseases and Related Health Problems, 10th Revision
| Title | Gender | DLB (%) | AD (%) | P value | Cognition | DLB (%) | AD (%) | P value | Living place | DLB (%) | AD (%) | P value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Depression |
Male |
6.3 |
3.8 |
0.020 |
MMSE ≥ 22 |
6.3 |
5.2 |
0.350 |
Own house |
7.0 |
4.5 |
0.006 |
| Female |
8.7 |
4.8 |
0.005 |
MMSE < 22 |
7.4 |
3.5 |
0.001 |
Nursing home |
9.3 |
3.9 |
0.068 |
|
| Anxiety |
Male |
3.4 |
1.8 |
0.031 |
MMSE ≥ 22 |
3.3 |
2.7 |
0.464 |
Own house |
3.2 |
2.6 |
0.372 |
| Female |
3.2 |
3.0 |
0.901 |
MMSE < 22 |
3.3 |
2.7 |
0.528 |
Nursing home |
4.0 |
2.8 |
0.469 |
|
| Behavioral disorders |
Male |
3.4 |
2.6 |
0.381 |
MMSE ≥ 22 |
2.4 |
1.9 |
0.471 |
Own house |
2.9 |
1.8 |
0.079 |
| Female |
3.2 |
1.6 |
0.071 |
MMSE < 22 |
3.7 |
2.0 |
0.062 |
Nursing home |
6.7 |
4.1 |
0.362 |
|
| Bipolar affective disorders |
Male |
0.5 |
0.5 |
0.702 |
MMSE ≥ 22 |
0.6 |
0.5 |
0.689 |
Own house |
0.9 |
0.4 |
0.185 |
| Female |
1.2 |
0.5 |
0.129 |
MMSE < 22 |
1.1 |
0.4 |
0.105 |
Nursing home |
0 |
1.0 |
1 |
|
| Sleep disorders |
Male |
3.9 |
2.5 |
0.094 |
MMSE ≥ 22 |
2.7 |
2.0 |
0.339 |
Own house |
2.7 |
1.6 |
0.040 |
| Female |
0.8 |
1.1 |
1 |
MMSE < 22 |
2.2 |
1.1 |
0.124 |
Nursing home |
2.7 |
1.4 |
0.325 |
|
| Syncope |
Male |
7.1 |
6.7 |
0.789 |
MMSE ≥ 22 |
6.9 |
7.4 |
0.782 |
Own house |
7.5 |
7.2 |
0.740 |
| Female |
7.5 |
7.4 |
0.950 |
MMSE < 22 |
7.8 |
6.9 |
0.579 |
Nursing home |
5.3 |
7.7 |
0.471 |
|
| Stroke |
Male |
8.7 |
6.0 |
0.043 |
MMSE ≥ 22 |
6.9 |
5.3 |
0.193 |
Own house |
8.4 |
5.1 |
0.001 |
| Female |
7.9 |
4.8 |
0.025 |
MMSE < 22 |
9.3 |
5.0 |
0.002 |
Nursing home |
8.0 |
7.1 |
0.772 |
|
| Cerebral hemorrhage |
Male |
1.8 |
1.6 |
0.732 |
MMSE ≥ 22 |
1.2 |
1.2 |
0.547 |
Own house |
1.8 |
1.4 |
0.410 |
| Female |
1.2 |
1.3 |
1 |
MMSE < 22 |
1.9 |
1.7 |
0.807 |
Nursing home |
0 |
1.8 |
0.613 |
|
| Epilepsy |
Male |
1.6 |
1.5 |
0.958 |
MMSE ≥ 22 |
1.2 |
1.3 |
1 |
Own house |
1.8 |
1.3 |
0.287 |
| Female |
2.0 |
1.2 |
0.242 |
MMSE < 22 |
2.2 |
1.2 |
0.165 |
Nursing home |
1.3 |
2.4 |
1 |
|
| Migraine | Male |
0.5 |
0.2 |
0.249 |
MMSE ≥ 22 |
0.9 |
0.4 |
0.165 |
Own house |
0.7 |
0.3 |
0.138 |
| Female | 1.6 | 0.4 | 0.580 | MMSE < 22 | 1.1 | 0.2 | 0.034 | Nursing home | 2.7 | 0.2 | 0.045 |
Univariate comparisons were performed using either the chi-square or Fisher’s exact test wherever appropriate. Statistically significant differences (P < 0.05) in bold. AD, Alzheimer’s disease; DLB, dementia with Lewy bodies; MMSE, Mini-Mental State Examination.