Table 2.

Emergency Department versus initial ICU performance of functional and structural biomarkers in acute kidney injury diagnosis

Biomarkers	Emergency Department	ICU	P -value
Plasma creatinine	0.72 (0.61 to 0.83)	0.69 (0.57 to 0.81)	0.15
Plasma cystatin C	0.68 (0.56 to 0.80)	0.64 (0.52 to 0.77)	0.09
Plasma NGAL	0.75 (0.64 to 0.87)	0.80 (0.68 to 0.90)	0.37
Urinary NGAL	0.68 (0.55 to 0.82)	0.77 (0.66 to 0.88)	0.04
Urinary cystatin C	0.60 (0.45 to 0.74)	0.73 (0.61 to 0.85)	0.004
Urinary GGT	0.55 (0.40 to 0.70)	0.69 (0.56 to 0.82)	0.01
Urinary α-GST	0.32 (0.15 to 0.49)	0.32 (0.18 to 0.46)	0.79
Urinary π-GST	0.46 (0.28 to 0.65)	0.52 (0.37 to 0.67)	0.62
Urinary alkaline phosphatase	0.50 (0.35 to 0.65)	0.57 (0.43 to 0.71)	0.06
Urinary albumin	0.44 (0.29 to 0.59)	0.54 (0.40 to 0.68)	0.08

Data expressed as area under curve with 95% confidence interval. NGAL, neutrophil gelatinase-associated lipocalin; GGT, gamma-glutamyltranspeptidase; GST, glutathione-S-transferase.