. 2014 Oct 20;57(22):9598–9611. doi: 10.1021/jm501284e

Table 4. Summary of Testing of Compounds 1–3 and Sunitinib for Metabolic Stability in Human, Murine, and Rat Microsomes^a.

name	human t_1/2 (min)	mouse t_1/2 (min)	rat t_1/2 (min)
sunitinib	44.1	12.3	26.5
1	10.4	1.3	6.8
2	7.3	0	NT
3	0	2.0	1.8

t_1/2 = half-life.

Table 4. Summary of Testing of Compounds 1–3 and Sunitinib for Metabolic Stability in Human, Murine, and Rat Microsomesa.