Table 5. Summary of Calculations of Ligand Efficiency Indices^a.

name	fTHP-15 Ki (M)	pKi	PSA (Ǻ2/100)	MW (kDa)	BEI	SEI
1	3.30 × 10–6	5.5	0.44	0.292	18.8	12.5
2	8.00 × 10–7	6.1	0.45	0.272	22.4	13.5
3	1.50 × 10–6	5.8	0.71	0.316	18.4	8.2
4	6.00 × 10–8	7.2	0.82	0.41	17.6	8.8
5	1.00 × 10–8	8.0	0.78	0.426	18.8	10.3
6	1.19 × 10–3	2.9	0.49	0.075	39.0	6.0
7 (idealized compd)	1.00 × 10–9	9.0	0.5	0.333	27.0	18

^aBEI = binding efficiency index. SEI = surface-binding efficiency index.