Table 4.
GO Analysis for the Genes with Top 5% Translocation Occurrences
| Category | GO Term | GO ID | C | O | E | R | rawP | adjP |
|---|---|---|---|---|---|---|---|---|
| Biological Process | Translational initiation | GO:0006413 | 152 | 12 | 2.79 | 4.29 | 2.42 × 10−5 | 0.0142 |
| Cellular macromolecular complex disassembly | GO:0034623 | 177 | 13 | 3.25 | 3.99 | 2.41 × 10−5 | 0.0142 | |
| Macromolecular complex disassembly | GO:0032984 | 182 | 13 | 3.35 | 3.88 | 3.23 × 10−5 | 0.0142 | |
| Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | GO:0000184 | 119 | 10 | 2.19 | 4.57 | 6.84 × 10−5 | 0.0226 | |
| Cellular protein complex disassembly | GO:0043624 | 156 | 11 | 2.87 | 3.83 | 0.0001 | 0.0264 | |
| Serine family amino acid metabolic process | GO:0009069 | 31 | 5 | 0.57 | 8.77 | 0.0002 | 0.0378 | |
| Protein complex disassembly | GO:0043241 | 161 | 11 | 2.96 | 3.72 | 0.0002 | 0.0378 | |
| Molecular Function | Structural constituent of ribosome | GO:0003735 | 157 | 14 | 3.04 | 4.6 | 2.24 × 10−6 | 0.0006 |
| Methyltransferase activity | GO:0008168 | 188 | 12 | 3.64 | 3.3 | 0.0003 | 0.0207 | |
| Immunoglobulin binding | GO:0019865 | 19 | 4 | 0.37 | 10.87 | 0.0004 | 0.0207 | |
| Transferase activity, transferring one-carbon groups | GO:0016741 | 194 | 12 | 3.76 | 3.19 | 0.0004 | 0.0207 | |
| mRNA binding | GO:0003729 | 91 | 7 | 1.76 | 3.97 | 0.0019 | 0.0492 |
Note.—C, the number of reference genes in the GO term; O, the number of genes in the gene set and also in the GO term; E, expected number in the GO term; R, ratio of enrichment (O/E); rawP, P value from hypergeometric test; adjP, P value adjusted by the multiple test adjustment.