Table 5.
Conserved and Overrepresented GO Terms for Genes with HCP and LCP in Six Higher Vertebrates
| GO ID | Conservationa | Subontology | GO Term Description |
|---|---|---|---|
| Overrepresented among genes with HCP | |||
| 0000122 | 4 | BP | Regulation of transcription from RNA polymerase promoter |
| 0003676 | 4 | MF | Nucleic acid binding |
| 0003677 | 4 | MF | DNA binding |
| 0003723 | 4 | MF | RNA binding |
| 0004672 | 4 | MF | Protein kinase activity |
| 0004930 | 4 | MF | G-protein coupled receptor activity |
| 0005634 | 4 | CC | Nucleus |
| 0005730 | 4 | CC | Nucleolus |
| 0006915 | 4 | BP | Apoptotic process |
| 0016021 | 4 | CC | Integral to membrane |
| 0016301 | 4 | MF | Kinase activity |
| 0043234 | 4 | CC | Protein complex |
| 0043565 | 5 | MF | Sequence-specific DNA binding |
| 0044212 | 4 | MF | Transcription regulatory region DNA binding |
| 0045892 | 4 | BP | Negative regulation of transcription, DNA-dependent |
| 0045893 | 4 | BP | Positive regulation of transcription, DNA-dependent |
| Overrepresented among genes with LCP | |||
| 0004869 | 4 | MF | Cysteine-type endopeptidase inhibitor activity |
| 0004984 | 4 | MF | Olfactory receptor activity |
| 0006955 | 4 | BP | Immune response |
| 0006958 | 5 | BP | Complement activation, classical pathway |
| 0006974 | 4 | BP | Response to DNA damage stimulus |
| 0007596 | 4 | BP | Blood coagulation |
| 0007601 | 4 | BP | Visual perception |
| 0008009 | 4 | MF | Chemokine activity |
| 0008270 | 4 | MF | Zinc ion binding |
| 0009897 | 4 | CC | External side of plasma membrane |
| 0015711 | 4 | BP | Organic anion transport |
| 0032729 | 4 | BP | Positive regulation of interferon-gamma production |
Note.—CC, cellular component; BP, biological process; MF, molecular function.
aThe number of higher vertebrate species for which the corresponding GO term is overrepresented.