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. 2014 Nov 28;12(Suppl 2):S3. doi: 10.1186/1479-5876-12-S2-S3

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Copyright © 2014 Roca et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Oxidative stress in COPD. Upper panel: Muscle oxidative stress. Individual and mean group effects of an 8-week endurance training program on protein carbonylation (left) and protein nitration (right) in the vastus lateralis of healthy subjects (controls) and patients with COPD. At baseline (rest, pre-training measurements), COPD patients showed higher nitroso-redox disequilibrium than healthy subjects. A trend toward a decrease in oxidative stress was observed after training in COPD patients [28]. Bottom panel: Association between muscle and blood. COPD patients at baseline (rest, pre-training) showed an association of protein carbonylation levels between skeletal muscle and blood [28] (reproduced from[28]with permission).