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. 2014 Nov 22;15:458. doi: 10.1186/1745-6215-15-458

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© Sivaprasad et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Flow diagram of the CLEOPATRA trial. The flow diagram shows the patient flow through the period of the trial and includes the mechanistic evaluation done at one site only.