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(a) Luciferase plasmid transfection efficiency and (b) cytotoxicity of reducible DBM-alkyne and non-reducible low, medium, and high MW polyplexes at N/P ratios = 5 and 10. Naked DNA and bPEI (25 kD) controls are included for comparison. Data is presented as mean ± SD, n = 4. Statistically significant (P<0.05) differences are indicated with a (*).
