Table 1. Parameters of the model.

Parameter	Definition and value(s)
	replication rate and affinity of the strand,
	the initial replication rate and affinity of the strand,
	number of vesicles in the population,
	initial number of molecules per vesicle,
	number of replicator types,
	number of mutant classes,
	number of monomers per macromolecule,
	maximal number of replication complexes,
	kinetic parameter of conversions ,
	kinetic parameter of conversions ,
	fixed concentration of the input material ,
	degradation rate of macromolecules,
	mutation rate, and
	mutational variability, parameter of the Poisson distribution,
	mutational variability, parameter of the normal distribution,
	strength of trade-off,