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Examples of possible effects of reactive oxygen and nitrogen radicals (for review see Dröge, 2002)
| Positive effects | Negative effects as “oxidative stress” |
|---|---|
| Signal transduction (NO) | Cell wall damage (ROS) |
| Stimulation of angiogenesis (NO) | Oxidation of DNA and proteins (O) |
| Influence on immune cells | Oxidation of lipids in cell bilayers (HO) |
| Proliferation of keratinocytes | Influence on cell respiration (O3) |
| Smooth muscle relaxation (NO) | |
| Control of ventilation | |
| Antimicrobial effects (H2O2) |
