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Effect of R. fasciculatum on scratching behavior in ICR mice. R. fasciculatum (200 mg/kg) was orally administered 1 h before compound 48/80 (50 μg/kg) intradermally injection. Scratching behaviors was counted as one incident of scratching for 30 min. Statistical evaluation of the results was performed by ANOVA with a Tukey post hoc test. Each datum represents the means ± S.D. of experiments (#p<0.05 vs. control group, *p<0.05 vs. compound 48/80 or histamine-treated group).
