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. 2014 Nov 29;14:99. doi: 10.1186/s12896-014-0099-3

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© Paul et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Stability and traceability of mAb aggregate standards. The stability of NaCl-induced mAb1 (A + B) and mAb2 (C + D) aggregates was investigated. B is an enlargement of A, D is an enlargement of C. (E) Stability of FT-induced mAb1 using MAbPac SEC-1. (F) Stability of FT-induced mAb2 aggregates using Yarra SEC-4000. (G) Traceability of NaCl-induced mAb2 aggregates using MAbPac SEC-1. (H) Traceability of FT-induced mAb2 aggregates using Yarra SEC-4000 under cell culture conditions.