Figure 5. Sun plot of (p<0.01) results for ABCG rs2231142, coded allele C.
This SNP has been previously reported to be associated with uric acid levels. Significant SNP-phenotype associations (p<0.01) are plotted clockwise with the smallest p-value result at the top. The length of the each line corresponds to the –log(p-value) of each result, with the longest line representing the most significant result for this SNP, meeting our PheWAS replication criteria for inclusion. Study, transformed (LN +1) or untransformed (none) phenotype description, self-reported race-ethnicity, and direction of effect are listed for each association. This SNP was associated with a number of phenotypes in this study including uric acid levels (as previously published) in non-Hispanic whites (NHW) and Mexican Americans (MA), protoporphyrin levels in non-Hispanic whites and Mexican Americans, and diastolic blood pressure in Mexican Americans.