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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: JACC Heart Fail. 2014 Oct 8;2(6):623–629. doi: 10.1016/j.jchf.2014.06.007

Table 2. Unadjusted and Adjusted Survival Differences Between ICD and Control Groups at Five Years by Number of Comorbidities.

No. of Comorbidities Unadjusted Adjusted


Median Survival Difference
(ICD – Control)
95% CI Median Survival Difference
(ICD – Control)
95% CI
0 0.11 (0.05 to 0.17) 0.13 (0.06 to 0.19)

1 0.12 (0.07 to 0.18) 0.13 (0.07 to 0.19)

2 0.13 (0.08 to 0.18) 0.13 (0.08 to 0.18)

3 0.11 (0.06 to 0.16) 0.11 (0.06 to 0.15)

4 0.06 (-0.01 to 0.14) 0.06 (0.00 to 0.14)

5 0.00 (-0.13 to 0.12) 0.00 (-0.10 to 0.12)

6 -0.06 (-0.19 to 0.07) -0.05 (-0.18 to 0.09)

No patient had all 7 comorbidities. Posterior probability of interaction between treatment and comorbidity, p < 0.01 (unadjusted and adjusted).

CI = confidence interval; ICD = implantable cardioverter-defibrillator.