Table 1. Characteristics of Study Participants.
|
No AR (n = 264, 51.7%) |
AR (n = 247, 48.3%) |
|
|---|---|---|
| Baseline characteristics | ||
| Age (years) | 10.2 (9.9, 10.5) | 10.5 (10.1, 10.8) |
| Female sex | 126 (47.7%) | 113 (45.8%) |
| Parental education (>high school) | 205 (77.7%) | 204 (82.6%) |
| Higher household income (>$15K/year) | 80 (31.6%) | 89 (36.8%) |
| Private/employer-based health insurance | 77 (29.2%) | 94 (38.1%)* |
| Asthma | 92 (34.9%) | 176 (71.3%)** |
| Leukotriene inhibitor in prior 6 months | 19 (7.2%) | 49 (19.8%)** |
| Inhaled corticosteroids in prior 6 months | 24 (9.1%) | 64 (25.9%)** |
| Atopic history | ||
| Eczematous rash, ever | 59 (22.4%) | 104 (42.1%)** |
| Family history | ||
| Parental history of allergic rhinitis | 40 (15.2%) | 57 (23.2%)* |
| Parental history of asthma | 111 (42.2%) | 145 (58.7%)** |
| Parental history of eczema | 4 (1.5%) | 8 (3.3%) |
| Home environment | ||
| Number of older siblings | 1.8 (1.6, 2.0) | 1.6 (1.4, 1.8) |
| Shared bedroom | 155 (58.7%) | 121 (49.0%)* |
| History of daycare | 48 (18.3%) | 63 (25.9%)* |
| Signs of mold/mildew | 88 (33.5%) | 119 (48.2%)** |
| Dog at home | 132 (50.4%) | 131 (53.0%) |
| Cat at home | 32 (12.3%) | 21 (8.5%) |
| Seeing rats or mice | 81 (30.7%) | 57 (23.1%) |
| Skin test reactivity | ||
| ≥1 allergen | 143 (54.2%) | 247 (100.0%)** |
| Total number positive skin tests | 2.8 (2.3-3.3) | 5.6 (5.1-6.0)** |
| Dust mite mix | 47 (17.9%) | 108 (43.9%)** |
| B. tropicalis | 81 (31.5%) | 179 (73.7%)** |
| Cockroach | 47 (18.0%) | 106 (43.6%)** |
| Mouse | 39 (14.8%) | 72 (29.2%)** |
| Dog | 42 (15.9%) | 82 (33.2%)** |
| Cat | 68 (25.8%) | 103 (41.7%)** |
| Mold mix | 25 (9.5%) | 37 (15.0%) |
| Alternaria | 44 (16.7%) | 75 (30.4%)** |
| Mixed trees | 59 (22.4%) | 83 (33.6%)* |
| Mixed grasses | 28 (12.2%) | 49 (21.9%)* |
| Mugwort sage | 22 (9.6%) | 43 (19.8%)** |
| Ragweed | 73 (27.7%) | 131 (53.0%)** |
| Home allergen levels1 | ||
| Log Der p (μg/g) | 4.2 (3.7, 4.9) | 4.8 (4.1, 5.5) |
| Log Bla g 2 (U/g) | 1.9 (1.6, 2.3) | 1.8 (1.5, 2.2) |
| Log Mus m 1 (ng/g) | 12.7 (9.7, 16.6) | 8.5 (6.3, 11.4)* |
| Log Can f 1 (μg/g) | 0.19 (0.15, 0.25) | 0.16 (0.12, 0.21) |
| Log Fel d 1 (μg/g) | 0.04 (0.03, 0.06) | 0.03 (0.02, 0.04) |
| Microbial associated molecular patterns1 | ||
| Log glucan (μg/mg) | 0.14 (0.11, 0.17) | 0.15 (0.12, 0.19) |
| Log peptidoglycan (μg/mg) | 0.014 (0.009, 0.02) | 0.015 (0.01, 0.02) |
| Log endotoxin (EU/mg) | 34.8 (30.6, 39.6) | 36.2 (31.1, 42.2) |
Values are presented as number (%) or mean (95% CI).
1
Presented as geometric means (95% CI). Difference between subjects with and without AR on univariate analysis at
*
P<0.05,
**
P<0.005.