Table 2. Multivariate analysis of mouse allergen level and AR by mouse sensitization status.
All Subjects | Unadjusted (n = 511) |
Adjusted Model 1A (n = 511) |
Adjusted Model 2A (n = 328) |
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OR (95% CI) | P-val | OR (95% CI) | P-val | OR (95% CI) | P-val | |
Mus m 1 (ng/g)1 | 0.84 (0.70, 1.00) | .049 | 0.75 (0.62, 0.92) | .005 | 0.72 (0.57, 0.92) | .009 |
Endotoxin1 | 1.11 (0.64, 1.92) | .703 | --- | --- | 1.22 (0.66, 2.24) | .528 |
Health insurance type | 1.49 (1.03, 2.16) | .034 | 1.66 (1.10, 2.52) | .017 | 1.61 (0.91, 2.83) | .100 |
Asthma | 4.63 (3.19-6.74) | <.001 | 6.40 (4.20, 9.73) | <.001 | 5.08 (3.01, 8.59) | <.001 |
Shared Bedroom | 0.68 (0.48, 0.96) | .028 | 0.50 (0.33, 0.76) | .001 | 0.44 (0.26, 0.73) | .002 |
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Sensitized to Mouse |
Unadjusted (n = 111) |
Adjusted Model 1B (n = 111) |
Adjusted Model 2B (n = 76) |
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Mus m 1 (ng/g)1 | 0.78, 0.52, 1.19) | .256 | 0.71 (0.44, 1.13) | .150 | 0.79 (0.41, 1.51) | .470 |
Endotoxin1 | 0.83 (0.28, 2.52) | .748 | --- | --- | 0.89 (0.26, 3.05) | .858 |
Health insurance type | 0.94 (0.41, 2.15) | .881 | 0.99 (0.39, 2.50) | .976 | 0.86 (0.24, 3.12) | .823 |
Asthma | 4.79 (2.07, 11.12) | <.001 | 6.56 (2.48, 17.37) | <.001 | 4.62 (1.48, 14.47) | .009 |
Shared Bedroom | 0.78 (0.35, 1.71) | .531 | 0.61 (0.24, 1.52) | .286 | 0.63 (0.21, 1.96) | .428 |
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Not Sensitized to Mouse |
Unadjusted (n = 400) |
Adjusted Model 1C (n = 400) |
Adjusted Model 2C (n = 252) |
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| ||||||
Mus m 1 (ng/g) 1 | 0.88 (0.72, 1.07) | .204 | 0.79 (0.63, 0.99) | .040 | 0.74 (0.56, 0.98) | .033 |
Endotoxin1 | 1.27 (0.66, 2.44) | .475 | --- | --- | 1.42 (0.68, 2.95) | .344 |
Health insurance type | 1.72 (1.13, 2.61) | .011 | 1.97 (1.22, 3.17) | .005 | 2.10 (1.10, 4.02) | .025 |
Asthma | 4.80 (3.12, 7.37) | <.001 | 6.84 (4.21, 11.14) | <.001 | 5.54 (2.96, 10.38) | <.001 |
Shared Bedroom | 0.64 (0.43, 0.95) | .026 | 0.44 (0.27, 0.72) | .001 | 0.35 (0.19, 0.65) | .001 |
All models adjusted for age, sex, and variables listed; model 2 additionally adjusted for endotoxin level (EU/mg).
Per each log10 unit increment.