Figure 4. Principal component analysis (PCA) of methylation measurements in cardiomyocyte and non-cardiomyocyte cells isolated from intact SHR and BN cardiac tissue.

(A) Projection of samples onto the first two principal components (PC) of the methylation measurements. (B) Comparison of loadings of the 1^st PC (strain separation) of PCA of methylation measurements done in each cell population separately.