Figure 3. Antibodies were unable to clear virus from persistently infected Rag1^−/− and µMT mice, and IFNγ, TNF and IL-6 levels were persistently elevated in persistently infected Rag1^−/− mice.

(A) Rag1^−/− mice day 485 post infection (n = 4) and µMT mice day 550 post infection (n = 4) were given 200 µl immune serum (neutralization titer 1/2560) i.p. on day 0 and viraemia determined on the indicated days. (B) Serum cytokine levels measured in Rag1^−/− mice at the indicated times post-infection (n = 3/4 mice per time point). (Data for IFNα day 1 & 2 and day 60 & 120, and day 200 & 265 for the other cytokines were combined, as n = 2 for each one of these times).