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. 2014 Dec 4;9(12):e113231. doi: 10.1371/journal.pone.0113231

Figure 3. Distinct genes are deregulated in C. elegans mutants lacking active OGT-1, OGA-1, or PMK-1 after 6 hours of pathogen exposure.

Figure 3

(A) Venn diagram of genes deregulated in ogt-1(ok1474) (red), oga-1(ok1207) (green), and pmk-1(km25) (blue) on OP50 vs. N2. (B) Categories of 387 commonly deregulated genes enriched according to DAVID analysis of microarray samples from A. (C) Heat map of relative levels of genes differentially regulated in mutant backgrounds compared to N2 on OP50 and those deregulated within individual mutants upon pathogen exposure. cpr-2, fmo-2, ilys-3, clec-60, and clec-52 [11], mtl-1, nspe-5, vhp-1, abf-2, and cyp-35A4 [55], spp-20 and cyp-35A3 [30], ilys-2 [11], [28], cnc-7 [55], [56], cyp-34A2 [57], tir-1 [58], [59], exc-5 [11], [55], irg-2 [29], Y75B8A.28 [60], [61], Y41C4A.11 [62], pgp-1 [53].