Figure 5. Demonstration of ex vivo murine IVD genetic recombination.

mT/mG mice IVDs were cultured for 10 days in the presence of (a) standard culture conditions, (b) control adenovirus, or (c) cre-recombinase expressing adenovirus. Images are 20× magnification Slides are counterstained with DAPI (blue). Red fluorescence represents no genetic recombination, green fluorescence represents successful genetic recombination, and yellow fluorescence represents an ongoing genetic recombination event.