Table 5. Clinical events in follow-up.
Events | High-dose statin n (%) | Control n (%) | P |
Stable | |||
Death | 12(1.6) | 13(2.7) | 0.67 |
Spontaneous MI | 7(1.0) | 7(1.3) | 0.50 |
TVR | 31(4.2) | 32(6.6) | 0.23 |
MACE | 50(6.8) | 52(10.7) | 0.12 |
ACS | |||
Death | 3(0.4) | 9(1.3) | 0.12 |
Spontaneous MI | 15(2.2) | 20(3.0) | 0.40 |
TVR | 16(2.4) | 34(5.0) | 0.01 |
MACE | 34(5.0) | 63(9.3) | 0.003 |
Mixed presentation | |||
Death | 1(0.1) | 1(0.1) | 0.50 |
Spontaneous MI | 1(0.1) | 0(0) | 0.51 |
TVR | 0(0) | 0(0) | NA |
MACE | 2(0.2) | 1(0.1) | 0.67 |
Statin-naive | |||
Death | 13(1.1) | 20(1.6) | 0.28 |
Spontaneous MI | 21(1.7) | 24(2.0) | 0.80 |
TVR | 41(3.4) | 59(4.9) | 0.09 |
MACE | 75(6.2) | 103(8.5) | 0.02 |
Prior low-dose statin | |||
Death | 3(0.5) | 3(0.8) | 0.25 |
Spontaneous MI | 2(0.3) | 3(0.8) | 0.07 |
TVR | 6(0.9) | 7(1.7) | 0.04 |
MACE | 11(1.7) | 13(3.3) | 0.003 |
Overall | |||
Death | 16(0.7) | 23(1.2) | 0.15 |
Spontaneous MI | 23(1.1) | 27(1.4) | 0.37 |
TVR | 47(2.2) | 66(3.5) | 0.02 |
MACE | 86(4.0) | 116(6.1) | 0.002 |
Spontaneous MI = spontaneous myocardial infarction; ACS = acute coronary syndrome;
TVR = target vessel revascularization; MACE = major adverse cardiovascular events;
NA = not available.