Table 2. Summary of transcripts (29 probe sets for 26 genes) dysregulated in the overlap of comparisons between dorsal trichoblastomas versus tail papillomas and dorsal trichoblastomas and facial papillomas.

AffymetrixID	*DL vs. TL	p-value	q-value	*DL vs. FL	p-value	q-value	IPA ID	Gene	Description	Location	Family
10353028	1.2142	0.0003	0.0025	1.2483	0.0005	0.0214	10353028	Vcpip1	valosin containing protein (p97)/p47 complex interacting protein 1	Cytoplasm	peptidase
10360720	−1.1487	0.0123	0.0267	−1.217	0.0018	0.0391	10360720	Wdr26	WD repeat domain 26	Cytoplasm	other
10364038	1.2426	0.0164	0.033	1.4241	0.0013	0.0337	10364038	Upb1	ureidopropionase, beta	Cytoplasm	enzyme
10368199	−1.4208	0.0177	0.0349	−2.2868	0.0005	0.0214	10368199	Myb	v-myb myeloblastosis viral oncogene homolog (avian)	Nucleus	transcription regulator
10421810	1.2775	0.0031	0.0102	1.3348	0.0024	0.0455	10421810	Rgcc	regulator of cell cycle	Cytoplasm	other
10434806	1.192	0.0038	0.0117	1.3013	0.0023	0.0443	10434806	Lpp	LIM domain containing preferred translocation partner in lipoma	Nucleus	other
10436451	−1.3819	0.002	0.0075	−1.8319	0.0008	0.0274	10436451	Stx19	syntaxin 19	Other	other
10436967	1.2058	0.0163	0.0329	1.257	0.0024	0.045	10436967	Cbr1	carbonyl reductase 1	Cytoplasm	enzyme
10443391	−1.1728	0.0106	0.0241	−1.3165	0.0027	0.0478	10443391	Mapk14	mitogen-activated protein kinase 14	Cytoplasm	kinase
10445574	1.3044	0.0014	0.0061	1.434	0.0025	0.0462	10445574	Cul7	cullin 7	Cytoplasm	other
10454286	−1.8277	0.0003	0.0026	−1.6974	0.0008	0.027	10454286	Mapre2	microtubule-associated protein, RP/EB family, member 2	Cytoplasm	other
10455395	−1.4012	0.0011	0.0051	−1.5692	0.0018	0.04	10455395	Spink5	serine peptidase inhibitor, Kazal type 5	Extracellular Space	other
10489092	1.2599	0.001	0.005	1.2368	0.0018	0.0401	10489092	Soga1	suppressor of glucose, autophagy associated 1	Extracellular Space	other
10489831	1.1783	0.0003	0.0028	1.1251	0.0016	0.0374	10489831	Stau1	staufen, RNA binding protein, homolog 1 (Drosophila)	Cytoplasm	transporter
10491272	−1.2368	0.0285	0.0493	−1.4175	0.0009	0.0282	10491272	Gpr160	G protein-coupled receptor 160	Plasma Membrane	G-protein coupled receptor
10495001	1.162	0.0102	0.0234	1.2775	0.001	0.0297	10495001	Rsbn1	round spermatid basic protein 1	Nucleus	other
10500122	−1.1594	0.0132	0.0281	−1.5018	0.0004	0.0196	10500122	Bnipl	BCL2/adenovirus E1B 19 kD interacting protein like	Cytoplasm	other
10530819	−1.5511	0.0007	0.004	−1.7695	0.0016	0.0375	10530819	Hopx	HOP homeobox	Nucleus	transcription regulator
10531323	1.1408	0.0179	0.0353	1.2426	0.0019	0.0414	10531323	G3bp2	GTPase activating protein (SH3 domain) binding protein 2	Nucleus	enzyme
10537026	−1.234	0.0186	0.0362	−2.5491	0.0001	0.0093	10537026	Cpa4	carboxypeptidase A4	Extracellular Space	peptidase
10561837	1.1674	0.0158	0.0322	1.2687	0.0016	0.0374	10561837	Znf146	zinc finger protein 146	Nucleus	other
10569923	−1.1647	0.0133	0.0282	−1.6133	0.0009	0.028	10569923	Lrrc8e	leucine rich repeat containing 8 family, member E	Other	other
10573803	1.217	0.0122	0.0266	1.4573	0.0027	0.0477	10573803	Cyld	cylindromatosis (turban tumor syndrome)	Nucleus	transcription regulator
10583647	−1.1434	0.0071	0.018	−1.2512	0.0008	0.0266	10583647	Dnm2	dynamin 2	Plasma Membrane	enzyme
10595856	1.2002	0.0191	0.0369	1.4473	0.0022	0.0434	10595856	Slc25a36	solute carrier family 25 (pyrimidine nucleotide carrier), member 36	Cytoplasm	transporter
10597162	−1.1947	0.0149	0.0307	−1.4012	0.0008	0.0265	10597162	Klhl18	kelch-like family member 18	Other	other

Several oncogenes and cell cycle regulatory genes are identified. However, while statistically significant, fold changes in all cases are relatively minor suggesting a great deal of interaction may be necessary for viral induced tumors to differentiate into benign and productive papillomas rather than locally aggressive cancers. (*Fold changes; p-value and q-value<0.05).