Table 1. Patient and clinical characteristics.
No-BPD | BPD (moderate to severe) | p | |
Total infants | 11 | 11 | |
Total samples | 13 | 25 | |
Gestational age (weeks)* | 28+3 (27–29+4) | 27+5 (25+4–29+2) | 0.45 |
Birth weight (g)* | 1120 (960–1250) | 905 (798.8–1120) | 0.14 |
Prolonged rupture of membranes (>24 hours)∧ | 1 (10) | 2 (22) | 1.0 |
Antenatal steroids (≥24 hours)∧ | 9 (82) | 9 (82) | 1.0 |
Caesarean delivery∧ | 5 (45) | 6 (55) | 1.0 |
Exogenous surfactant replacement∧ | 11 (100) | 11 (100) | 1.0 |
Mechanical ventilation-days* | 1.0 (1.0–1.75) | 6.5 (5.0–15.5) | 0.004 |
Peak PIP* | 17.0 (15.75–21.5) | 22.0 (20.0–25.0) | 0.07 |
Peak FiO2* | 21.0 (21.0–30.5) | 41.0 (32.5–70.5) | 0.002 |
Patent ductus arteriosus∧ | 5 (45) | 8 (73) | 0.39 |
Peak C-Reactive Protein (CRP)* | 4.0 (1.5–14.5) | 18.0 (6.5–82.0) | 0.08 |
Lung Infection (16sRNA)∧ | 2 (18) | 4 (36) | 0.64 |
*Values shown are medians (inter-quartile range) with superscript numbers indicating days in addition to gestation in weeks; ∧ values shown are numbers of infants (percentage of total in group).