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. 2014 Dec 4;9(12):e114469. doi: 10.1371/journal.pone.0114469

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© 2014 Galabova et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Titers (ODmax/2) against huPCSK9 (n = 8/group) generated upon 4 vaccinations in biweekly intervals. (B) TC levels in treated animals (nmol/L), compared to control. Bars and error bars represent mean values ±SEM; significance compared to control values (****p<0.0001) was obtained by a 2-tailed Student’s t-test.