Fig. 7.

Workflow specific aspects of protein group regulation: A, Comparison of protein groups identified as being regulated using a FDR cut-off of less than 1% uniquely by in-solution protein IEF (blue circle) or protein fractionation-free (yellow circle) workflows or in common by both workflows; (intersection); and, B, breakdown of the data presented in A to depict the contributions of spectral count and intensity data to the assessment of regulation in both workflows.