Fig. 9.

Relationships between protein groups regulated by hRSV infection of A549 cells and potentially involved key regulators. Protein groups found to be regulated using a FDR cut-off of less than 1% were used to interrogate IPA and Interferome for evidence of regulation by IFNs, TNF-α, and/or NF-κB. Protein groups are displayed as triangular nodes with apices oriented upwards or downwards according to whether they were up- or down-regulated in infected cells, respectively. Nodes are colored using the displayed color coding system to indicate the potential influences of individual or multiple key regulators as indicated by IPA and/or Interferome. Central key regulator nodes are represented as circles. The protein groups falling into each category of regulation are presented numerically within each node and specifically identified in Supplemental Table 6.