Fig. 2.

Global protein and PTM regulation observed in the three subcellular fractions and corresponding transcriptional regulation. Z normalized spectral count data for significant regulated proteins in A, nuclear, B, cytosolic, and C, mitochondrial fractions. Z normalized mziXIC values of significantly regulated PTMs in D, nuclear, E, cytosolic, and F, mitochondrial fractions. “C” indicates control and “T” treated. “SC” is the range of total number of spectral counts. “M” is the log ratio for mRNA expression. “E” is the evidence group: For a given protein “E = 1” means that the protein has at least one peptide spectra assignment matching uniquely, “E = 2” means that the protein belongs to a group of proteins that cannot be distinguished based on the MS data and have at least one peptide spectra assignment matching uniquely to the group, and “E = 3” means a protein that belongs to a group of proteins that share peptide spectra assignments of which none belongs to evidence groups one or two.