Table 1.

Characteristics of included studies

Study characteristic						Rufinamide	Placebo
Study number	Authors	Year	Multicentre	Randomized	Reported adverse events	Patients treated	Patients treated
1	Palhagen et al. [15]	2001	9	1:1 ratio	Fatigue, headache and dizziness	25	25
2	Glauser et al. [5]	2008	36	Blocks of four, centre level	Somnolence	74	64
3	Elger et al. [14]	2010	Yes*	1:1 ratio	Fatigue, headache, dizziness and somnolence	262	133
4	Biton et al. [11]	2011	65	1:1 ratio	Fatigue, headache, dizziness and somnolence	176	180
5	Brodie et al. [10]	2009	48	1:1 ratio	Fatigue, headache, dizziness and somnolence	156	157

^*Number of centres is not mentioned in the original article.