Table 1.
Baseline demographics of enrolled subjects eligible for pharmacokinetic similarity assessment
| PF-05280014 | Trastuzumab-EU | Trastuzumab-US | |
|---|---|---|---|
| Number of subjects | 34 | 35 | 32 |
| Mean age ± SD (years) | 34.5 ± 10.7 | 36.1 ± 9.5 | 35.3 ± 9.2 |
| Race | |||
| White | 13 | 7 | 8 |
| Black | 14 | 22 | 15 |
| Other | 7 | 6 | 9 |
| Mean weight ± SD (kg) | 79.7 ± 11.2 | 86.3 ± 11.3 | 81.4 ± 11.0 |
| Mean height ± SD (cm) | 175.9 ± 6.7 | 177.8 ± 8.0 | 177.3 ± 7.4 |
| Mean BMI ± SD (kg m−2) | 25.8 ± 3.1 | 27.2 ± 2.6 | 25.9 ± 3.0 |
BMI, body mass index [weight (0.01 height)−2; with weight in kg and height in cm]; SD, standard deviation.