Figure 7.

Mean count (SEM) profiles of lymphocytes and eosinophils (A) and CD4+ total, naïve, central memory (Tcm), and memory (mem) T cells, and Tcm cells expressing low or high levels of α₄β₇ receptors (B) in all subjects treated with AMG 181 or placebo. (A) , Eosinophil, active; , Eosinophil, placebo; , Lymphocyte, active; , Lymphocyte, placebo; Active (n = 5–50); Placebo (n = 6–19). (B) , CD4 + total, active; , CD4 + total, placebo; , CD4 + naive, active; , CD4 + naive, placebo; , CD4 + Tcm, active; , CD4 + Tcm, placebo; , CD4 + mem, active; , CD4 + mem, placebo; , α₄β₇ low CD4 + Tcm, active; , α₄β₇ low CD4 + Tcm, placebo; , α₄β₇ high CD4 + Tcm, active; , α₄β₇ high CD4 + Tcm, placebo; Active (n = 5–52); Placebo (n = 5–18)