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Summary of minimum cathepsin S (CatS) activity
| LY3000328 dose (mg) | Mean (SD) minimum CatS activity (μU ml−1) | Mean (SD) time of minimum CatS activity (h post-dose) |
|---|---|---|
| Placebo | 18.24 (4.47) | 5.1 (11) |
| 1 | 18.93 (2.13) | 4.3 (0.8) |
| 3 | 13.53 (2.11) | 4.3 (0.8) |
| 10 | 13.35 (1.73) | 4.3 (0.8) |
| 30 | 6.33 (1.69) | 4.7 (1.0) |
| 100 | 3.77 (0.83) | 3.3 (1.0) |
| 300 | 0.97 (0.38) | 3.3 (1.0) |
