Relationship of 24 h urinary glucose excretion with fasting plasma glucose. Observed values are shown as separate symbols for each treatment; population predicted values are shown as separate lines for each treatment. , placebo/baseline; , empagliflozin 1 mg once daily; , empagliflozin 2.5 mg once daily; , empagliflozin 5 mg once daily, , empagliflozin 10 mg once daily, , empagliflozin 25 mg once daily; , empagliflozin 100 mg once daily