Figure 2. INPP5F regulates glioblastoma cell proliferation and self-renewal activities in vitro.
(A) INPP5F overexpression decreased glioblastoma cell proliferation, while INPP5F knockdown increased proliferation activity. (B) Analysis of self-renewal activity represents that INPP5F overexpressing GSCs reduced sphere formation and INPP5F knockdown increased sphere forming activity. (C) INPP5F overexpression shows a decreased colony forming activity. (NS: no significant; * p<0.05; ** p<0.001; compared to control). Error bars represent standard deviation (S.D., experiment performed in triplicates).