Table 1.
Patient Characteristics (N=346)
| Characteristic | Stage IIIA (N=346) | Stage I and II (N=1294) |
|---|---|---|
| Female | 193 (56) | 752 (58) |
| Age, years (mean ± SD) | 65 ± 10 | 69 ± 10 |
| FEV 1, % predicted (mean ± SD) | 87 ± 18 | 89 ± 21 |
| Current or past smoker | 308 (89) | 1098 (85) |
| Neoadjuvant therapy | ||
| Yes | 195 (56) | 0 |
| Chemotherapy | 168 (49) | |
| Chemoradiation | 26 (8) | |
| Radiation | 1 (0.2) | |
| Procedure | ||
| Lobectomy | 265 (77) | 955 (74) |
| Pneumonectomy | 46 (13) | 17 (1) |
| Bilobectomy | 19 (5) | 22 (2) |
| Wedge | 10 (3) | 188 (15) |
| Segmentectomy | 5 (1) | 111 (9) |
| Histologic profile | ||
| Adenocarcinoma | 227 (66) | 995 (77) |
| Squamous cell | 70 (20) | 222 (17) |
| Other | 25 (7) | 45 (3) |
| Large cell | 18 (5) | 32 (2) |
| Adenosquamous | 5 (1) | 0 |
| Bronchioloalveolar carcinoma | 1 (0.2) | 0 |
| Adjuvant therapy | ||
| Yes | 187 (54) | 202 (16) |
| Chemotherapy | 127 (37) | 192 (15) |
| Radiation | 40 (12) | 1 (<1) |
| Chemotherapy + radiation | 20 (6) | 1 (<1) |
| Unknown | 15 (4) | 8 (1) |