Table 3.
Incense use and cardiovascular mortality in the Singapore Chinese Health Study, stratified by baseline history of CVD, smoking, or education level at baseline (1993–2011).a
Exposure | Participants | Person-years | CVD | CHD | Stroke | |||
---|---|---|---|---|---|---|---|---|
Deaths | HR (95% CI) | Deaths | HR (95% CI) | Deaths | HR (95% CI) | |||
Stratified by baseline CHD or strokeb | ||||||||
Without baseline CHD or stroke | ||||||||
Noncurrent use | 13,774 | 204,917 | 757 | 1.00 | 421 | 1.00 | 203 | 1.00 |
urrent use | 46,082 | 681,316 | 3,378 | 1.16 (1.07, 1.26) | 1,847 | 1.13 (1.01, 1.26) | 972 | 1.24 (1.06, 1.45) |
With baseline CHD or stroke | ||||||||
Noncurrent use | 863 | 10,447 | 230 | 1.00 | 142 | 1.00 | 50 | 1.00 |
urrent use | 2,538 | 30,081 | 678 | 1.00 (0.86, 1.17) | 441 | 1.04 (0.85, 1.27) | 156 | 1.06 (0.76, 1.48) |
Stratified by smoking statusc | ||||||||
Never-smokers | ||||||||
Noncurrent use | 10,954 | 165,511 | 582 | 1.00 | 314 | 1.00 | 160 | 1.00 |
urrent use | 32,976 | 499,294 | 2,144 | 1.12 (1.02, 1.23) | 1,137 | 1.10 (0.96, 1.25) | 672 | 1.26 (1.05, 1.51) |
Former smokers | ||||||||
Noncurrent use | 1,647 | 22,125 | 169 | 1.00 | 100 | 1.00 | 37 | 1.00 |
urrent use | 5,346 | 71,726 | 651 | 1.19 (1.00, 1.42) | 407 | 1.25 (1.00, 1.57) | 154 | 1.18 (0.81, 1.71) |
Current smokers | ||||||||
Noncurrent use | 2,036 | 27,728 | 236 | 1.00 | 149 | 1.00 | 56 | 1.00 |
urrent use | 10,298 | 140,377 | 1,261 | 1.05 (0.91, 1.22) | 744 | 1.00 (0.83, 1.20) | 302 | 1.03 (0.77, 1.38) |
Stratified by education leveld | ||||||||
No formal education | ||||||||
Noncurrent use | 2,333 | 33,063 | 272 | 1.00 | 151 | 1.00 | 74 | 1.00 |
urrent use | 15,000 | 215,540 | 1,650 | 0.98 (0.86, 1.11) | 884 | 0.93 (0.78, 1.11) | 519 | 1.13 (0.88, 1.45) |
Primary school | ||||||||
Noncurrent use | 5,065 | 73,625 | 383 | 1.00 | 223 | 1.00 | 94 | 1.00 |
urrent use | 22,985 | 336,371 | 1,844 | 1.14 (1.02, 1.27) | 1,068 | 1.10 (0.95, 1.27) | 484 | 1.30 (1.04, 1.63) |
≥ Secondary school | ||||||||
Noncurrent use | 7,239 | 108,676 | 332 | 1.00 | 189 | 1.00 | 85 | 1.00 |
urrent use | 10,635 | 159,485 | 562 | 1.25 (1.09, 1.44) | 336 | 1.28 (1.06, 1.53) | 125 | 1.17 (0.88, 1.55) |
aThe p for interactions between incense use (binary variable) and baseline CHD/stroke (binary variable) were 0.02, 0.15, and 0.28 for CVD, CHD, and stroke mortality, respectively. The p for interactions between incense use (binary variable) and smoking status (never, former, and current smokers) were 0.27, 0.21, and 0.21 for CVD, CHD, and stroke mortality, respectively. The p for interactions between incense use (binary variable) and education level (no formal education, primary school, and ≥ secondary school) were 0.03, 0.03, and 0.81 for CVD, CHD, and stroke mortality, respectively. bThe estimates were generated using Cox proportional hazards models, with adjustment for age at recruitment; year of recruitment; gender; dialect; education; BMI; alcohol consumption; years of smoking; amount of smoking; years since quitting smoking; moderate physical activity; duration of sleep; daily energy intake; dietary intake of vegetables, fruits, fiber, and polyunsaturated fatty acids; and self-reported history of physician-diagnosed hypertension, diabetes, and cancer. cThe estimates were generated using Cox proportional hazards models, with adjustment for age at recruitment; year of recruitment; gender; dialect; education; BMI; alcohol consumption; moderate activity; duration of sleep; daily energy intake; dietary intake of vegetables, fruits, fiber, and polyunsaturated fatty acids; and self-reported history of physician-diagnosed hypertension, diabetes, cancer, CHD, and stroke. dThe estimates were generated using Cox proportional hazards models, with adjustment for age at recruitment; year of recruitment; gender; dialect; BMI; alcohol consumption; years of smoking; amount of smoking; years since quitting smoking; moderate physical activity; duration of sleep; daily energy intake; dietary intake of vegetables, fruits, fiber, and polyunsaturated fatty acids; and self-reported history of physician-diagnosed hypertension, diabetes, cancer, CHD, and stroke. |