Figure 1.

Tip60 expression in the adult Drosophila brain. Frontal view of a wild-type (Canton S) adult Drosophila brain stained with an antibody to Tip60 (red) and counterstained with anti-ELAV antibody (green). Tip60 is widely expressed in the adult fly brain (A) including the MB lobes (A, arrow), with an expression pattern similar to the pan-neuronal ELAV protein (B and C). (A–C) Whole-brain reconstruction of individual confocal image slices. Bar, 100 μM. A single confocal plane through the MB at the level of the calyx (approximately the center of the Z-stack) in flies that express mCD8-GFP under the control of OK107-GAL4 driver shows Tip60 expression in Kenyon cell (KC) nuclei with a halo of GFP expression in the cell membrane and calyx (dendritic processes) (D–F).