Figure 2.

Tip60 is expressed in the MB lobes. Representative confocal images of adult MB lobes in wild-type (Canton S) Drosophila brain stained with Tip60 antibody (A and D) and costained with antibodies to either Fasciclin II (Fas II) (B) or Trio (E) antibodies. Fas II is a cell adhesion molecule that is expressed strongly in the MB α/β lobes and weakly in the γ lobe. Trio is a Dbl family protein that activates Rho family GTPases and is expressed strongly in the α′/β′ lobes and weakly in the γ lobe. Tip60 is expressed in all the lobes of the MB and colocalizes with Fas II and Trio in the α/β (C) and α′/β′ (F) lobes, respectively. Tip60 also colocalizes with Fas II and Trio in the γ lobes (C and F).