Table 2.
Patient characteristics at time of CMR*
| All (n = 23) | RF < 20% (n = 11) | RF > 20% (n = 12) | P value | |
|---|---|---|---|---|
| Age (mean ± SD) | 83 ± 6 | 83 ± 7 | 83 ± 5 | 0.82 |
| NYHA class (mean ± SD) | 3.5 ± 0.8 | 3.4 ± 0.9 | 3.7 ± 0.7 | 0.37 |
| ΔNYHA class since TAVR (median[IQR]) | 1 (0, 1) | 1 (−1, 1) | 0 (0, 1) | 0.77 |
| STS-PROM (%; mean ± SD) | 7.8 ± 4.6 | 6.3 ± 2.3 | 9.0 ± 5.7 | 0.16 |
| ΔSTS-PROM since TAVR (%; median[IQR]) | 0 (−0.5, 1.7) | 0 (−1.1, 0) | 0.8 (−0.4, 3.0) | 0.15 |
| Laboratory | ||||
| Creatinine (mg/dl; median[IQR]) | 1.29 (1.00, 1.84) | 1.11 (1.00, 1.37) | 1.61 (1.06, 2.63) | 0.011 |
| ΔCreatinine since TAVR (mg/dl; median[IQR]) | 0.1 (−0.06, 0.39) | 0.03 (−0.08, 0.19) | 0.36 (0.10, 0.55) | 0.13 |
| BNP (pg/ml; median[IQR])) | 496 (252, 1335) | 432 (235, 546) | 1038 (339, 1948) | 0.05 |
| ΔBNP since TAVR (pg/ml; median[IQR]) | 0 (−419, 199) | 0 (−411, 85) | 68 (−441, 240) | 0.73 |
| Echocardiography | ||||
| Circumferential extent (%; mean ± SD) | 34.2 ± 18.4 | 23.3 ± 18.2 | 44.3 ± 11.9 | 0.003 |
| CMR | ||||
| Ejection fraction (%; mean ± SD) | 48 ± 12 | 47 ± 10 | 49 ± 14 | 0.78 |
| Other valve disease greater than mild† | 14 (61) | 4 (36) | 10 (83) | 0.04 |
*All results are presented as n (%) unless otherwise noted.
†Includes mitral and tricuspid regurgitation.
BNP = brain natriuretic peptide, CMR = cardiovascular magnetic resonance, IQR = interquartile range, NYHA = New York Heart Association, PVL = paravalvular leak, RF = regurgitant fraction, STS-PROM = Society of Thoracic Surgeons predicted risk of mortality, TAVR = transcatheter aortic valve replacement, TTE = transthoracic echocardiography.