. 2014 Nov 3;15(11):505. doi: 10.1186/s13059-014-0505-0

Table 4.

Genes encoding proteins containing eukaryotic motifs not previously described

*L. pneumophila*	*L. longbeachae*	*L. micdadei*	*L. hackeliae*	*L. fallonii* (LLAP10)	Product	Eukaryotic motif
lpg0095/lpp0109	llo3322	lmi1217	lha1000	lfa0120	Cytosolic IMP-GMP specific 5'-nucleotidase	HAD-superfamily hydrolase, 5'-nucleotidase
lpg0301/lpp0379				lfa0312#	Protein of unknown function	DM9 repeat
lpg0971/lpp1033					Apyrase	Nucleoside phosphatase
lpg1328 ^a/lpp1283				lfa0766	Protein of unknown function	Thaumatin
lpg1798 ^a/lpp1761	llo0991				Protein of unknown function	RhoGTPase
lpg1905/lpp1880	llo1247	lmi2007	lha1318	lfa0744	Apyrase	Nucleoside phosphatase
			lha0318		Protein of unknown function	DM9 repeat
	llo3014			lfa2606	Protein of unknown function	DM9 repeat
			lha0498		Protein of unknown function	Synaptobrevin/V-snare
				lfa3165	Protein of unknown function	Synaptobrevin/V-snare
	llo0044				Protein of unknown function	Thaumatin
		lmi1344			Protein of unknown function	Thaumatin
			lha2013		Protein of unknown function	Thaumatin
		lmi0545	lha2362	lfa2256	Protein of unknown function	DH/RhoGEF
	llo0042			lfa0022	Putative serine carboxypeptidase	Peptidase S28
				lfa1003	Protein of unknown function	Mitochondrial substrate/solute carrier repeat
		lmi0716			Protein of unknown function [ARM repeat]	Clathrin/coatomer_adaptine_like
		lmi1174			Protein of unknown function [HEAT-REPEAT DOMAIN] [F-box domain]	Clathrin/coatomer_adaptine_like
		lmi0037			Protein of unknown function [coiled-coil]	RhoGTPase
		lmi0496		lfa2567 ^b	Protein of unknown function	T-complex protein 10
		lmi3046	lha3117 ^b		Protein of unknown function	Peptidase C65

^aGene encoding a protein that has been demonstrated to be secreted by the Dot/Icm secretion system. ^bOrthologous proteins in which the corresponding motif is not present.