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Impact of sex on DNA methylation and expression in human pancreatic islets of genes previously associated with insulin secretion. (A-D) DNA methylation and expression of genes with previously known function in insulin secretion located on autosomal chromosomes (A,B) or the X chromosome (C,D) in human pancreatic islets. Data are presented as mean ± standard error of the mean. Asterisks indicate q <0.05 for the DNA methylation data and P <0.05 for the gene expression data.
