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. 2014 Aug 27;21(1):79. doi: 10.1186/s12929-014-0079-x

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© Benen et al.; licensee BioMed Central 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Induction of low neutralizing antibody titers in rabbit sera after immunization with gp41 derivatives. After removal of anti-cell antibodies, sera were tested in neutralization assays with two viral strains. Dilutions mediating inhibition of 50% infection (ID50) subtracted by ID50 of pre-bleed sera are shown. Sera of all groups were tested against tier-1 isolates (A) MW965.26 (clade C) and (B) SF162 (clade B). Asterisks mark significant difference between groups (p < 0.05).