Table 1.
P. falciparum proteins with conserved phosphatase related superfamily domains (accession numbers as per http://www.plasmoDB.org , version 9.2 and superfamily according to NCBI CDD search)
| ID | Description | Length |
|---|---|---|
| MPP ((Metallophosphatase)) superfamily | ||
| PF3D7_0314400 | serine/threonine protein phosphatase, putative | 308 |
| PF3D7_0802800 | serine/threonine protein phosphatase, putative | 604 |
| PF3D7_0918000 | glideosome-associated protein 50,secreted acid phosphatase (GAP50) | 396 |
| PF3D7_0925400 | protein phosphatase-beta | 466 |
| PF3D7_0927700 | serine/threonine protein phosphatase, putative | 312 |
| PF3D7_1018200 | serine/threonine protein phosphatase, putative | 2166 |
| PF3D7_1206000 | protein phosphatase, putative | 304 |
| PF3D7_1355500 | serine/threonine protein phosphatase (PP5) | 658 |
| PF3D7_1403900 | phosphatase, putative | 298 |
| PF3D7_1406700 | phosphatase, putative | 194 |
| PF3D7_1414400 | serine/threonine protein phosphatase (PP1) | 304 |
| PF3D7_1423300 | serine/threonine protein phosphatase (PP7) | 959 |
| PF3D7_1464600 | phosphatase, putative | 1442 |
| PF3D7_1466100 | protein serine/threonine phosphatase | 889 |
| PF3D7_1469200 | protein phosphatase, putative | 358 |
| PF3D7_0107800 | DNA repair exonuclease Mre11, putative | 1233 |
| PF3D7_0912400 | conserved Plasmodium protein, unknown function | 446 |
| PF3D7_1340600 | RNA lariat debranching enzyme, putative (DBR1) | 575 |
| HP (Histidine phosphatases) superfamily | ||
| PF3D7_1430300 | acid phosphatase, putative | 2657 |
| PF3D7_0208400 | conserved Plasmodium protein, unknown function | 2010 |
| PF3D7_0310300 | phosphoglycerate mutase, putative | 1165 |
| PF3D7_0413500 | phosphoglucomutase-2 (PGM2) | 295 |
| PF3D7_1120100 | phosphoglycerate mutase, putative (PGM1) | 250 |
| HAD_like (Haloacid Dehalogenase) superfamily | ||
| PF3D7_0515900 | protein phosphatase, putative | 328 |
| PF3D7_0726900 | protein phosphatase, putative | 519 |
| PF3D7_1012700 | protein phosphatase, putative | 1438 |
| PF3D7_1226100 | hydrolase/phosphatase, putative | 316 |
| PF3D7_1355700 | protein phosphatase, putative | 1288 |
| PF3D7_1363200 | bifunctional polynucleotide phosphatase/kinase (PNKP) | 462 |
| PF3D7_0715000 | 4-nitrophenylphosphatase (PNPase) | 322 |
| PF3D7_0817400 | conserved Plasmodium protein, unknown function | 739 |
| PF3D7_1118400 | haloacid dehalogenase-like hydrolase, putative | 306 |
| PF3D7_0303200 | HAD superfamily protein, putative | 1162 |
| PAP2_like (2-phosphatidic acid phosphatases) superfamily | ||
| PF3D7_0625000.1 | phosphatidic acid phosphatase (PAP) | 439 |
| PF3D7_0625000.2 | phosphatidic acid phosphatase | 461 |
| PF3D7_0805600 | apicoplast phosphatidic acid phosphatase, putative | 308 |
| PP2Cc (Protein phosphatases 2c domain) superfamily | ||
| PF3D7_1138500 | protein phosphatase 2c | 924 |
| PF3D7_0410300 | protein phosphatase, putative | 906 |
| PF3D7_0520100 | protein phosphatase, putative | 706 |
| PF3D7_0810300 | protein phosphatase, putative | 550 |
| PF3D7_0810500 | protein phosphatase, putative | 303 |
| PF3D7_1009600 | protein phosphatase, putative | 488 |
| PF3D7_1135100 | protein phosphatase, putative | 689 |
| PF3D7_1249300 | protein phosphatase, putative | 1027 |
| PF3D7_1309200 | protein phosphatase 2c-like protein, putative | 827 |
| PF3D7_1455000 | protein phosphatase, putative | 410 |
| PF3D7_1208900 | conserved Plasmodium protein, unknown function | 1442 |
| EEP (Exonuclease-endonuclease Phosphatases) superfamily | ||
| PF3D7_0319200 | endonuclease/exonuclease/phosphatase family protein, putative | 906 |
| PF3D7_0705500 | inositol-phosphate phosphatase, putative | 2814 |
| PF3D7_1111600 | endonuclease/exonuclease/phosphatase family protein, putative | 744 |
| PF3D7_0107200 | carbon catabolite repressor protein 4, putative | 337 |
| PF3D7_0305600 | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 617 |
| PF3D7_1238600 | sphingomyelin phosphodiesterase, putative | 393 |
| PF3D7_1363500 | DNase I-like protein, putative | 836 |
| PF3D7_1430600 | exodeoxyribonuclease III, putative | 876 |
| Syja_N (SacL homology domain) superfamily | ||
| PF3D7_0705500 | inositol-phosphate phosphatase, putative | 2814 |
| PF3D7_0802500 | inositol phosphatase, putative | 1419 |
| PF3D7_1354200 | inositol-polyphosphate 5-phosphatase, putative | 803 |
| PTPLA (Protein tyrosine phosphatase-like protein) superfamily | ||
| PF3D7_1331600 | protein tyrosine phosphatase, putative | 228 |
| RHOD (Rhodanese Homology Domain) superfamily | ||
| PF3D7_1305500 | protein phosphatase, putative | 771 |
| PF3D7_1206400 | rhodanese like protein, putative | 346 |
| CYTH-like_Pase (Triphosphate Tunnel Metaloenzyme Phosphatases) superfamily | ||
| (Apicomplexan) | ||
| PF3D7_0322100 | RNA triphosphatase (Prt1) | 591 |
| PTH2_family (Peptidyl-tRNA hydrolase, type 2) superfamily | ||
| PF3D7_0610500 | conserved protein, unknown function | 123 |
| PTPc (Protein Tyrosine phosphatase) superfamily | ||
| PF3D7_0309000 | dual specificity phosphatase (YVH1) | 575 |
| PF3D7_1113100 | protein tyrosine phosphatase (PRL) | 218 |
| PF3D7_1127000 | protein phosphatase, putative | 287 |
| PF3D7_1455100 | protein phosphatase, putative | 171 |
| Nucleoside Phosphatase superfamily | ||
| PF3D7_1431800 | apyrase, putative | 874 |
| PF3D7_1322000 | adenosine-diphosphatase, putative | 565 |