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. Author manuscript; available in PMC: 2014 Dec 5.
Published in final edited form as: Neuroimaging Clin N Am. 2009 Nov;19(4):517–526. doi: 10.1016/j.nic.2009.08.008

Fig. 3.

Fig. 3

Functional diffusion mapping of a 9L brain tumor model treated with BCNU chemotherapy. The panel shows examples of FDM maps and corresponding FDM plots following a 0 (a and b), 0.5 (c and d), 1 (d and e) and 2×LD10 (f and g) doses of BCNU. These results demonstrated the quantitative nature of diffusion MRI since a dose dependent increase in tumor cell kill correlated with an increase in the number of voxels that had positive change in diffusion (red) compared to pre-treatment values. Courtesy of Moffat et al. [36].